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Split Biosciences Awarded Small Business Innovation Research (SBIR) Grant from the National Science Foundation

Small Business Innovation Research Program Provides Seed Funding for R&D 


Seattle, WA- July 2, 2019 – Split Biosciences has been awarded a National Science Foundation (NSF) Small Business Innovation Research (SBIR) grant for $225,000 to further research and development (R&D) work towards democratizing single-cell RNA sequencing. 

The Seattle-based company is developing a family of kits that enable researchers to perform scalable single-cell sequencing experiments. Unlike existing single cell technologies, Split Bio’s kits use only standard molecular biology equipment and do not require the upfront purchase of a custom instrument. The company’s innovative approach to single-cell sequencing is based upon a combinatorial barcoding strategy published in Science in 2018. 

The one-year grant will pay for continued development on the company’s single-cell RNA-sequencing kit. The kit will enable researchers to sequence up to 100,000 cells across 48 different samples in a single experiment. Researchers interested in participating in an early access program can find more information at splitbio.com. 



About the National Science Foundation's Small Business Programs: America’s Seed Fund powered by NSF awards $200 million annually to startups and small businesses, transforming scientific discovery into products and services with commercial and societal impact. Startups working across almost all areas of science and technology can receive up to $1.5 million in non-dilutive funds to support research and development (R&D), helping de-risk technology for commercial success. America’s Seed Fund is congressionally mandated through the Small Business Innovation Research (SBIR) program. The NSF is an independent federal agency with a budget of about $8.1 billion that supports fundamental research and education across all fields of science and engineering.

Completion of Seed Financing 

Seattle, WA - October 12, 2018 - Split Biosciences, a Seattle based single-cell analysis company, today announced the recent completion of its seed financing.


Split Biosciences is a University of Washington spinout and will use the financing to build upon the groundbreaking single-cell RNA-sequencing technology--SPLiT-seq--published in Science in early 2018. The technology addresses current limitations of single-cell RNA-sequencing through the use of multiple rounds of in-situ combinatorial barcoding.